Human growth hormone diseases can be determined through administering tests on individuals. Human growth hormone is the hormone responsible for growth and plays a role in the metabolism processes in the human body. It is secreted by the pituitary gland and considered to be a major product of the gland. Human growth hormone is commonly referred to as somatotropin.

HGH diseases are present in forms of excess or deficiency of the hormone. Basically, HGH deficiency gives low stature to an individual and excessive HGH is related to gigantism. There are different methods of treating HGH diseases. The treatment of an individual with HGH disease can be more effective if the disease is identified earlier.

These Tests that are used to find out if an individual has HGH disease, one of these tests is the Growth Hormone Simulation Test (GHST). GHST is used to determine the individual’s ability to produce HGH. There are several purposes of the GHST test. Some of these are:

• To identify delayed puberty
• To monitor the functioning of the pituitary gland
• To help in the analysis of pituitary tumors and gigantism
• To assess HGH therapy

Before adhering to the test, an individual must abstain from any activity that might affect his HGH levels. There are drugs that must be avoided because they decrease or increase the HGH level. Amphetamines, dopamines and corticosteroids are drugs to be avoided before the test. The patient must also avoid being stressed, avoid exercising or going into a diet because these factors affect the HGH level. The patient must also abstain from eating or drinking after midnight before the test.

A normal person with a low level of HGH before the test doesn’t necessarily mean that he has a disease. The level of HGH of a patient is bound to increase after simulation. If the level doesn’t increase after simulation, then the patient is recommended for other tests and will be examined for other symptoms of HGH disease.

GHST involves the injection of insulin-induced hypoglycemia or HGH releasing factor to stimulate the secretion of HGH.  Blood samples are taken five times after the injection of a stimulant. These blood samples are used in determining the HGH level of a patient.

During the test, a patient may experience sweating and sleepiness. Minor distress is also expected to be felt after the test. There are also cases of ketosis and a disturbance of the body’s acid-base balance that is associated with GHST. A patient may also experience too much bleeding, fainting, blood accumulation under the skin and infection.  However, all of these side effects can be avoided with proper and keen observation form the administering doctor.

The GHST is one of the frequently used tests in determining HGH diseases.  However, it is merely a test to determine the HGH level and the pituitary glands capacity to produce HGH. A fixed HGH level is used as parameter to determine if a patient has HGH deficiency. Normal results vary with sex and age. If a patient falls below the normal results, he is recommended for diagnosis and treatment.

Undergoing a test is not the cure for HGH diseases. The tests are only the start of treating HGH diseases. All people are at risk of acquiring Human growth diseases. People who notice abnormalities in their height or muscle mass should immediately submit themselves for a test. It is never too late to prevent HGH diseases.

Human growth hormone plays an important role in human growth processes and metabolism processes. HGH is secreted in bursts by the anterior part of the pituitary gland. HGH levels are determined by this secretion and HGH levels affect the growth of an individual. A normal amount of HGH is required in every individual to optimize his chances for growth development. However, not all people are fortunate to have the exact amount of HGH. The incapacity to have normal HGH levels lead to HGH diseases. These diseases are characterized by low stature or excessive height.

The treatment and cure for these HGH diseases has been the subject of research for a long period of time. Human growth hormone was discovered by Dr. Harvey Cushing in 1912. The HGH was widely discussed and explained all over scientific journals in the next ten years. Maben purified growth hormone from a cadaver and injected it to the boy to enhance the deficiency. Because of Maben’s successful treatment, researchers extensively looked at all possibilities of treating HGH diseases. Cadaver GH became a popular method in treating HGH diseases.

The method of using cadaver GH for treating HGH diseases was decreased when majority of the patients treated with it was diagnosed with Creutzfeldt-Jakob disease (CJD) in 1985 – a very rare neurodegenerative disease that is transmissible and usually ends in death within eight months of acquiring the disease. CJD was given large attention because it had appeared as a side effect of cadaver GH.

Researchers explored different methods to treat HGH diseases without the threat of acquiring CJD. In 1985, the Orphan Drug Act was passed in Congress as a financial benefit for pharmaceutical companies to develop drugs for HGH diseases. It was also during this time that gene splicing together with genetic engineering was invented. Genetic engineering made it possible for scientists to categorize proteins and to clone them.

Genetic engineering process entails producing a desired protein through inserting a gene into laboratory cell lines. This is called recombinant gene technology. Genentech made the first recombinant human growth hormone (rhGH) in 1985 and was approved by the U.S Food and Drug Administration in October that year.

Genentech’s rhGH Protropin was almost identical to the DNA chain of HGH except its code chain was off by one amino acid. This trivial disparity from the HGH didn’t affect the effectiveness of Protropin but offered other companies the possibility of competition. In 1986, an Indianapolis-based company, Eli Lily developed a HGH product, Humatrope that was identical to the 191 amino acid chain of HGH.

Genentech and Eli Lily battled for patent issues and exclusive rights of distribution and both cited Orphan Drug Act of 1985 as protection. The battle was settled in court with the court permitting both companies to distribute their products and prohibiting other companies to distribute HGH products. Both companies earned a lot of money in marketing their respective products. However, the big news for HGH products was not the treatment of HGH diseases but the possibility to reverse aging.

Human growth hormone products and supplements are now openly circulated in the market. These products come in different forms; pills, oral sprays or by injections.

The methods of treating human growth hormone diseases have come a long way from cadaver GH. There are different supplements and products which are available in the market and do not have fatal side effects like CJD. Nonetheless, it is still a long journey for HGH products to prove that they can truly reverse aging.

Somatotrophin is specific to every species which means that different species have different growth hormone. It is a peptide consisting of 191 amino acids. It is secreted in explosions and not secreted throughout the day. The secretion of growth hormone increases before sleeping. The amount of secretion of Somatotrophin, together with thyroid and sex hormones, affect the height of the individual. Aside from affecting growth, Somatotrophin also plays a role in controlling metabolism of carbohydrates, proteins and fat. Growth hormone is very important in every individual’s maintenance of body composition.

Human growth hormone is an important hormone in the human body. It is secreted by the pituitary gland that is located in the brain. The growth hormone is a major product of the pituitary gland and is specifically produced by somatotrophs in the anterior part. The growth hormone is often referred to as Somatotrophin and is responsible for controlling growth and has effects in metabolism processes.

The production of growth hormone is increased and decreased by certain factors. These factors include stress, nutrition, exercise and sleep. However, the primary regulators of HGH are growth hormone releasing hormone (GHRH), somatostatin and Ghrelin. GHRH stimulates the synthesis and production of the growth hormone. Somatostatin is a peptide produced by hypothalamus and stops growth hormone release in response to GHRH and other motivating factors. Ghrelin powerfully stimulates production of growth hormone through binding with somatotrophs.

Growth hormone has two distinct types of effects in the body. These effects are;

• Direct effects
• Indirect effects

Direct effects are the results of binding between growth hormone receptors and target cells. One example of this is the effect of growth hormone binding with fat cells which results in the breaking down of triglyceride in fat cells and prevents them from taking and circulating lipids. On the other hand, indirect effects are brought about by Insulin like growth factor-I (IGF-I). This hormone is secreted as a response to growth hormone. It is also one of the primary aides of growth hormone in affecting growth.

HGH together with IGF-I have significant roles in different processes in the body. Examples of these processes are:

• Growth of all tissues including repair
• Turning body fat into muscle
• Energy level improvement
• Bone strength
• Brain function

The body actively produces growth hormones during childhood and puberty years. This active production results to height increase in individuals. However, at the end of puberty years, secretion of growth hormone decreases. It continuously decreases as people grow older. The decrease in the production of growth hormone contributes to weakness of bones in older people and their loss of strength. In some cases, children are born with growth hormone abnormalities. Growth hormone deficiency results in low stature of an individual. Excessive growth hormones result in having too much height.

Human growth hormone is very important in as much that is has become the subject of research. Researchers are continuously finding ways to use growth hormones to reverse the aging process and increasing muscle mass. Several researchers and companies have produced HGH products. These products are mainly used in treating HGH diseases. They are available in injections, pills and oral sprays. These HGH products and supplements are also being used to combat age.

HGH products are induced into the body to increase the HGH secretion therefore making the user feel young again. However, the fact remains that age cannot be defeated and the aging process is inevitable for every human.

Human growth hormones role in the growth processes cannot be denied. It plays a major role in determining and reaching the ideal height for any individual. Nonetheless, the HGH is not only useful in the growth processes but in other processes of the body.

Because of its name, many people think that the only aim of the growth hormone is to stimulate growth processes. The HGH is not only confined to its role in growth processes, it also plays a lot of roles in many metabolism processes.

Metabolism is the breakdown of food into simple substances that can be taken by the body in certain processes. It is a chemical process that breaks down some substances so as to get energy and to process specific substances. Some of the roles of the growth hormone in metabolism are to deliver molecules, conserve sugars, build proteins and break down fat.

The growth hormone specifically plays a role in the following metabolism processes:

Protein metabolism

Fat metabolism

Carbohydrate metabolism

Protein metabolism concerns the breakdown of protein and differentiating the useful part from the excretion products. Growth hormone fuels the protein anabolism in tissues. This role of the GH is seen in the amino acid uptake, protein synthesis and oxidation of proteins.  In fat metabolism, the GH advances the operation of fat by motivating the breakdown of triglyceride and adipocytes oxidation. Carbohydrate metabolism concerns the breakdown of glucose into energy that will be used by the body.

This metabolism can be anaerobic or aerobic. The growth hormone aids in carbohydrate metabolism by maintaining the blood glucose level within the normal range. The GH is referred to as having an anti insulin activity due to the fact that it restrains the capabilities of the insulin to fuel uptake of glucose.

It is because of these metabolism processes that adults still need HGH when they reach old age. HGH is important in avoiding diabetes, chronic diseases and osteoporosis. Although HGH is continuously secreted for growth processes, growth processes cannot continue in adults because the bones have ceased to grow. It is in these metabolism processes that an individual can see the effects of HGH.

Some people tend to overlook these functions and focus on the functions of HGH in growth development. Nonetheless, the metabolic functions of the HGH should not be neglected because metabolism is as important as the growth processes. Every process in our body is important in maintaining a balanced body composition.

HGH metabolic roles are also important to adults and should not be neglected. Aging comes with the difficulty to eat, to chew and even to digest the food that you eat. Maintaining a normal level of HGH can give more benefit to adults. Throughout a man’s life, the human growth hormone level should be given utmost attention because they control important processes in the human body.

The functioning of HGH in metabolism processes is also affected by the level of HGH present in an individual. Health measures should be observed like avoiding stress, observing proper nutrition and doing exercises.

The growth and metabolism functions of the human growth hormone go hand in hand. While the HGH is the main controller of the growth processes, it doesn’t limit itself to that function. It also aids in the metabolism processes that also contributes to the growth processes. These functions of the HGH is a two way street: they benefit each other.